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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYH11
All Species:
31.82
Human Site:
Y499
Identified Species:
100
UniProt:
P35749
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35749
NP_002465.1
1972
227339
Y499
F
I
L
E
Q
E
E
Y
Q
R
E
G
I
E
W
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109425
1979
227586
Y502
F
I
L
E
Q
E
E
Y
Q
R
E
G
I
E
W
Dog
Lupus familis
XP_862291
1938
223405
Y499
F
I
L
E
Q
E
E
Y
Q
R
E
G
I
E
W
Cat
Felis silvestris
Mouse
Mus musculus
O08638
1972
227010
Y499
F
I
L
E
Q
E
E
Y
Q
R
E
G
I
E
W
Rat
Rattus norvegicus
Q9JLT0
1976
228947
Y499
F
I
L
E
Q
E
E
Y
Q
R
E
G
I
E
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508844
1972
227342
Y499
F
I
L
E
Q
E
E
Y
Q
R
E
G
I
E
W
Chicken
Gallus gallus
P10587
1979
228777
Y505
F
I
L
E
Q
E
E
Y
Q
R
E
G
I
E
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q99323
2057
236625
Y591
F
I
L
E
Q
E
E
Y
Q
R
E
G
I
E
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.5
96.1
N.A.
95.9
75.7
N.A.
94.3
89.8
N.A.
N.A.
N.A.
58.1
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
97.3
97.5
N.A.
98.5
88.3
N.A.
97.6
95.2
N.A.
N.A.
N.A.
74.8
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
100
0
100
100
0
0
0
100
0
0
100
0
% E
% Phe:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
100
0
0
0
0
0
0
0
0
0
0
100
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
100
0
0
0
100
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _